Research output per year
Research output per year
Personal profile
Education
2015 Seoul National University, Ph.D. in Biomedical Sciences
2010 Korea University, B.S. in Genetic Engineering
2010 Korea University, B.S. in Genetic Engineering
Professional Experience
2020.09 - current: Univerisy of Seoul, Department of Life Science, Assistant Professor
2016.05 - 2020. 08: Salk Institute for Biological Studies, Post-doctoral Researcher
2015.03 - 2016.04: Genomic Medicine Institute, Seoul National University, Post-doctoral Researcher
2016.05 - 2020. 08: Salk Institute for Biological Studies, Post-doctoral Researcher
2015.03 - 2016.04: Genomic Medicine Institute, Seoul National University, Post-doctoral Researcher
Major Research Achievements
[2023.07] Hur J, Kim H, Kim U, Kim GB, Kim J, Joo B, Cho D, Lee DS*, Chung AJ. Genetically Stable and Scalable Nanoengineering of Human Primary T Cells via Cell Mechanoporation. doi: 10.1021/acs.nanolett.3c01720. Nano Letters
[2022.12] Xu Z, Lee DS*, Chandran S, Le VT, Bump R, Yasis J, Dallarda S, Marcotte S, Clock B, Haghani N, Cho CY, Akdemir KC, Tyndale S, Futreal PA, McVicker G, Wahl GM, Dixon JR. Structural variants drive context-dependent oncogene activation in cancer. doi: 10.1038/s41586-022-05504-4. Nature
[2023.05] Nam CH, Youk J, Kim JY, Lim J, Park JW, Oh SA, Lee HJ, Park JW, Jeong SY, Lee DS*, Oh JW, Han J, Lee J, Kwon HW, Kim MJ, Ju YS. Widespread somatic L1 retrotransposition in normal colorectal epithelium. doi: https://doi.org/10.1038/s41586-023-06046-z. Nature
[2019.10] Lee DS*, Luo C*, Zhou J*, Chandran S, Rivkin A, Bartlett A, Nery JR, Fitzpatrick C, O’Connor C, Dixon JR, Ecker JR. Simultaneous profiling of 3D genome structure and DNA methylation in single human cells. doi: 10.1038/s41592-019-0547-z. Nature Methods.
[2014.12] Lee DS*, Shin JY, Tonge PD, Puri MC, Lee S, Park H, Lee WC, Hussein SM, Bleazard T, Yun JY, Kim J, Li M, Cloonan N, Wood D, Clancy JL, Mosbergen R, Yi JH, Yang KS, Kim H, Rhee H, Wells CA, Preiss T, Grimmond SM, Rogers IM, Nagy A, Seo JS. An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator. doi: 10.1038/ncomms6619 Nature Commun
[2022.12] Xu Z, Lee DS*, Chandran S, Le VT, Bump R, Yasis J, Dallarda S, Marcotte S, Clock B, Haghani N, Cho CY, Akdemir KC, Tyndale S, Futreal PA, McVicker G, Wahl GM, Dixon JR. Structural variants drive context-dependent oncogene activation in cancer. doi: 10.1038/s41586-022-05504-4. Nature
[2023.05] Nam CH, Youk J, Kim JY, Lim J, Park JW, Oh SA, Lee HJ, Park JW, Jeong SY, Lee DS*, Oh JW, Han J, Lee J, Kwon HW, Kim MJ, Ju YS. Widespread somatic L1 retrotransposition in normal colorectal epithelium. doi: https://doi.org/10.1038/s41586-023-06046-z. Nature
[2019.10] Lee DS*, Luo C*, Zhou J*, Chandran S, Rivkin A, Bartlett A, Nery JR, Fitzpatrick C, O’Connor C, Dixon JR, Ecker JR. Simultaneous profiling of 3D genome structure and DNA methylation in single human cells. doi: 10.1038/s41592-019-0547-z. Nature Methods.
[2014.12] Lee DS*, Shin JY, Tonge PD, Puri MC, Lee S, Park H, Lee WC, Hussein SM, Bleazard T, Yun JY, Kim J, Li M, Cloonan N, Wood D, Clancy JL, Mosbergen R, Yi JH, Yang KS, Kim H, Rhee H, Wells CA, Preiss T, Grimmond SM, Rogers IM, Nagy A, Seo JS. An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator. doi: 10.1038/ncomms6619 Nature Commun
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Epigenetic Regulations in Mammalian Cells: Roles and Profiling Techniques
Kim, U. & Lee, D. S., 28 Feb 2023, In: Molecules and Cells. 46, 2, p. 86-98 13 p.Research output: Contribution to journal › Short survey › peer-review
Open Access8 Scopus citations -
Foxp3 orchestrates reorganization of chromatin architecture to establish regulatory T cell identity
Liu, Z., Lee, D. S., Liang, Y., Zheng, Y. & Dixon, J. R., Dec 2023, In: Nature Communications. 14, 1, 6943.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Genetically Stable and Scalable Nanoengineering of Human Primary T Cells via Cell Mechanoporation
Hur, J., Kim, H., Kim, U., Kim, G. B., Kim, J., Joo, B., Cho, D., Lee, D. S. & Chung, A. J., 23 Aug 2023, In: Nano Letters. 23, 16, p. 7341-7349 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
In Vivo Stem Cell Imaging Principles and Applications
Hong, S., Lee, D. S., Bae, G. W., Jeon, J., Kim, H. K., Rhee, S. & Jung, K. O., 2023, In: International Journal of Stem Cells. 16, 4, p. 363-375 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Widespread somatic L1 retrotransposition in normal colorectal epithelium
Nam, C. H., Youk, J., Kim, J. Y., Lim, J., Park, J. W., Oh, S. A., Lee, H. J., Park, J. W., Won, H., Lee, Y., Jeong, S. Y., Lee, D. S., Oh, J. W., Han, J., Lee, J., Kwon, H. W., Kim, M. J. & Ju, Y. S., 18 May 2023, In: Nature. 617, 7961, p. 540-547 8 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations