Calculated based on number of publications stored in Pure and citations from Scopus
1997 …2023

Research activity per year

Personal profile

Education

1995 Michigan State University, Ph.D. in Zoology
1989 Hanyang University, M.S. in Genetic Engineering
1986 Seoul National University, B.S. in Agricultural Chemistry

Professional Experience

2021.03 - 2023.02 University of Seoul. School of Natural Sciences, Dean
2010.10 - Present University of Seoul. Dept. of Life Science. Professor
2005.10 - 2010.09 University of Seoul. Dept. of Life Science. Associate Professor
2001.09 - 2005.09 University of Seoul. Dept. of Life Science. Assistant Professor
2001.01 - 2001.08 Catholic University Research Professor
1997.03 - 2000.12 Columbia University (New York) Associate Researcher
1995.11 - 1997.02 SUNY at Stony Brook Post-doc

Research Interests

Wnt and Hippo signaling, Mechanisms of cancers and Alzheimer's disease

Major Research Achievements

[2022.08] Tan A, Prasad R, Lee C, and Jho EH*. Past, Present, and Future Perspectives of Transcription Factor EB (TFEB): Mechanisms of regulation and association in disease. Cell Death Differ. 29(8):1433-1449.
[2021.09] Kim S, Song G, Lee T, Kim M, Kwon H, Kim J, Jeong W, Lee U, Na C, Kang S, Kim W, Seong J, and Jho EH*. PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF1. Cell Death Differ. 28(9):2555-2570.
[2020.09] Jeong W, Kim S, Lee U, Zhong ZA, Savitsky M, Kwon H, Kim J, Lee T, Cho JW, Williams BO, Katanaev VL, Jho EH*. LDL receptor-related protein LRP6 senses the level of nutrient and regulates Hippo signaling. EMBO Reports 21(9):e50103
- A commentary for this work was presented in “News & Views” in EMBO reports.
- This work has been recommended in Faculty Opinions.
[2020.06] Kim J, Kwon H, Shin YK, Song G, Lee T, Kim Y, Jeong W, Lee U, Zhang X, Nam G, Jeung HC, Kim W, Jho EH*. MAML1/2 promote YAP/TAZ nuclear localization to enhance tumorigenesis. Proc Natl Acad Sci U S A. 117(24):13529-13540.
[2020.05] Kim Y, Kim W, Song Y, Kim JR, Cho K, Moon H, Ro SW, Seo E, Ryu YM, Myung SJ, Jho EH*. Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability. Proc Natl Acad Sci U S A. 114:4691-4696.
● Highlighted in Hepatic cell news – April 21, 2017


Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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