Personal profile
Education
1997 Stanford University, Ph.D. in Molecular Pharmacology
1998 Seoul National University, M.S. in Pharmaceutics
1986 Seoul National University, B.S. in Pharmaceutics
1998 Seoul National University, M.S. in Pharmaceutics
1986 Seoul National University, B.S. in Pharmaceutics
Professional Experience
2008.10 - current Univerisy of Seoul, Department of Life Science, Professor
2004.12 - 2005.11 Univerisy of Seoul, Department of Life Science, Department Chair
2003.10 - 2008.09 Univerisy of Seoul, Department of Life Science, Associate Professor
1997.09 - 2003.09 Univerisy of Seoul, Department of Life Science, Assistent Professor
1992.09 - 1997.06 Stanford Medical School, Department of Molecular Pharmacology, Research Assistant
1989.01 - 1991.09 Texas A&M University, Department of Biochemistry and Biophysics, Teaching and Research Assistant
2004.12 - 2005.11 Univerisy of Seoul, Department of Life Science, Department Chair
2003.10 - 2008.09 Univerisy of Seoul, Department of Life Science, Associate Professor
1997.09 - 2003.09 Univerisy of Seoul, Department of Life Science, Assistent Professor
1992.09 - 1997.06 Stanford Medical School, Department of Molecular Pharmacology, Research Assistant
1989.01 - 1991.09 Texas A&M University, Department of Biochemistry and Biophysics, Teaching and Research Assistant
Research Interests
Hypoxia, Gene expression, Epigenetics, Histone Methylation,
Major Research Achievements
[2022.07] G-J. Lee*, YJ Kim*, B. Park*, S.Yim*, C. Park, H. Roh, Y. Moon, JK. Seong, H. Park (2022/04/27) YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity. Cell Death & Disease 13(4) 407 (Co-corresponding author)
[2021.10] HJ. An*, Y. Kim*, S. Chang*, H. Kim, J. Song, H. Park, and I. Choi(2021.10) High-Spatial and Colourimetric Imaging of Histone Modifications in Single Senescent Cells Using Plasmonic Nanoprobes. Nature Communications 12(1) 5899 (Co-corresponding author)
[2019.10] B Park, S Chang, G-J. Lee, B. Kang, JK. Kim and H. Park (2019) Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis. Cell Death and Dis. 10(1), 16-27
[2017.11] S. Lee, J. Lee, S. Chae, Y. Moon, H-Y. Lee, B. Park, EG. Yang, D. Hwang, and H. Park (2017) Multi-dimensional histone methylations for coordinated regulation of gene expression under hypoxia. Nucleic Acids Res. 45 (20), 11643-11657 (Co-corresponding author)
[2008.11] SM. Choi, H-J. Cho, H. Cho, KH. Kim, JB. Kim and H. Park. (2008) Stra13/DEC1 and DEC2 Inhibit Sterol Regulatory Element Binding Protein-1c In a Hypoxia-Inducible Factor-Dependent Mechanism. Nucleic Acids Res 36(20) 6372-6385
[2021.10] HJ. An*, Y. Kim*, S. Chang*, H. Kim, J. Song, H. Park, and I. Choi(2021.10) High-Spatial and Colourimetric Imaging of Histone Modifications in Single Senescent Cells Using Plasmonic Nanoprobes. Nature Communications 12(1) 5899 (Co-corresponding author)
[2019.10] B Park, S Chang, G-J. Lee, B. Kang, JK. Kim and H. Park (2019) Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis. Cell Death and Dis. 10(1), 16-27
[2017.11] S. Lee, J. Lee, S. Chae, Y. Moon, H-Y. Lee, B. Park, EG. Yang, D. Hwang, and H. Park (2017) Multi-dimensional histone methylations for coordinated regulation of gene expression under hypoxia. Nucleic Acids Res. 45 (20), 11643-11657 (Co-corresponding author)
[2008.11] SM. Choi, H-J. Cho, H. Cho, KH. Kim, JB. Kim and H. Park. (2008) Stra13/DEC1 and DEC2 Inhibit Sterol Regulatory Element Binding Protein-1c In a Hypoxia-Inducible Factor-Dependent Mechanism. Nucleic Acids Res 36(20) 6372-6385
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Collaborations and top research areas from the last five years
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Hypoxia increases methylated histones to prevent histone clipping and heterochromatin redistribution during Raf-induced senescence
Chang, S., Moon, R., Nam, D., Lee, S. W., Yoon, I., Lee, D. S., Choi, S., Paek, E., Hwang, D., Hur, J. K., Nam, Y., Chang, R. & Park, H., 10 Feb 2025, In: Nucleic Acids Research. 53, 3, gkae1210.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
Moon, Y., Chae, S., Yim, S., Yang, E. G., Choe, J., Hyun, J., Chang, R., Hwang, D. & Park, H., 15 Jul 2022, In: iScience. 25, 7, 104517.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Gold and silver plasmonic nanoprobes trace the positions of histone codes
Choi, I., Song, J. & Park, H., 2022, In: BMB Reports. 55, 3, p. 111-112 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Synergistic effect of Aloe vera flower and Aloe gel on cutaneous wound healing targeting MFAP4 and its associated signaling pathway: In-vitro study
Razia, S., Park, H., Shin, E., Shim, K. S., Cho, E., Kang, M. C. & Kim, S. Y., 23 May 2022, In: Journal of Ethnopharmacology. 290, 115096.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity
Lee, G. J., Kim, Y. J., Park, B., Yim, S., Park, C., Roh, H., Moon, Y., Seong, J. K. & Park, H., Apr 2022, In: Cell Death and Disease. 13, 4, 407.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations