Research output per year
Research output per year
Personal profile
Education
2001 The Ohio State University, Ph.D. in Biochemistry (Ohio State Biochemistry Program)
1994 Seoul National University, M.S. in Chemistry (Biochemistry Major)
1992 Seoul National University, B.S. in Chemistry
1994 Seoul National University, M.S. in Chemistry (Biochemistry Major)
1992 Seoul National University, B.S. in Chemistry
Professional Experience
2017.09 - current: University of Seoul, Department of Life Science, Proferrsor
2012.09 - 2017.08: University of Seoul, Department of Life Science, Associate Proferrsor
2008.09 – 2012.08: University of Seoul, Department of Life Science, Assistant Proferrsor
2005.10 - 2008.08 Department of Biological Sciences, Stanford University Research Associate
2001.10 - 2005.09 Department of Biological Sciences, Stanford University Post-doctoral Research Fellow
2012.09 - 2017.08: University of Seoul, Department of Life Science, Associate Proferrsor
2008.09 – 2012.08: University of Seoul, Department of Life Science, Assistant Proferrsor
2005.10 - 2008.08 Department of Biological Sciences, Stanford University Research Associate
2001.10 - 2005.09 Department of Biological Sciences, Stanford University Post-doctoral Research Fellow
Research Interests
Lipocalin-2, Astrocyte, Ubiquitin, Protein degradation, Autophagy
Major Research Achievements
[2023.08] B. K. Jung, Y. Park, B. Yoon, J. S. Bae, S. W. Han, J. E. Heo , D. E. Kim*, K. Y. Ryu*, Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage. Autophagy, 19(8), 2296–2317, 2023.
[2022.10] S. W. Han, K. Y. Ryu, Increased clearance of non-biodegradable polystyrene nanoplastics by exocytosis through inhibition of retrograde intracellular transport. Journal of Hazardous Materials, 439, 129576, 2022.
[2021.07] B. Han*, B. K. Jung*, S. H. Park, K. J. Song, M. A. Anwar, K. Y. Ryu#, K. P. Kim#, Polyubiquitin gene Ubb is required for upregulation of Piwi protein level during mouse testis development. Cell Death Discovery, 7, 194, 2021.
[2022.10] S. W. Han, K. Y. Ryu, Increased clearance of non-biodegradable polystyrene nanoplastics by exocytosis through inhibition of retrograde intracellular transport. Journal of Hazardous Materials, 439, 129576, 2022.
[2021.07] B. Han*, B. K. Jung*, S. H. Park, K. J. Song, M. A. Anwar, K. Y. Ryu#, K. P. Kim#, Polyubiquitin gene Ubb is required for upregulation of Piwi protein level during mouse testis development. Cell Death Discovery, 7, 194, 2021.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Recent progress and future directions of the research on nanoplastic-induced neurotoxicity
Han, S. W., Choi, J. & Ryu, K. Y., Feb 2024, In: Neural Regeneration Research. 19, 2, p. 331-335 5 p.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations -
Alleviation of neurotoxicity induced by polystyrene nanoplastics by increased exocytosis from neurons
Han, S. W., Kim, T. Y., Bae, J. S., Choi, J. & Ryu, K. Y., 6 Aug 2023, In: Biochemical and Biophysical Research Communications. 668, p. 19-26 8 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Lipocalin-2: a therapeutic target to overcome neurodegenerative diseases by regulating reactive astrogliosis
Jung, B. K. & Ryu, K. Y., Oct 2023, In: Experimental and Molecular Medicine. 55, 10, p. 2138-2146 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations -
Mild Oxidative Stress Induced by Sodium Arsenite Reduces Lipocalin-2 Expression Levels in Cortical Glial Cells
Cho, Y. J., Park, S. H. & Ryu, K. Y., Nov 2023, In: International Journal of Molecular Sciences. 24, 21, 15864.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage
Jung, B. K., Park, Y., Yoon, B., Bae, J. S., Han, S. W., Heo, J. E., Kim, D. E. & Ryu, K. Y., 2023, In: Autophagy. 19, 8, p. 2296-2317 22 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations