Research output per year
Research output per year
Personal profile
Education
B.S.: Department of Genetic Engineering, Sungkyunkwan University
Ph. D.: Division of Interdisciplinary Bioscience & Bioengineering, POSTECH
Ph. D.: Division of Interdisciplinary Bioscience & Bioengineering, POSTECH
Professional Experience
(2017. 5. - 2022. 6.) Postdoc, Stem Cell Convergence Research Center (SCCRC), Korea Research Institute for Bioscience and Biotechnology (KRIBB)
(2022. 6. - 2024. 2.) Researcher, Stem Cell Convergence Research Center (SCCRC), Korea Research Institute for Bioscience and Biotechnology (KRIBB)
(2024. 3. - 2026. 2.) Senior Researcher, Stem Cell Convergence Research Center (SCCRC), Korea Research Institute for Bioscience and Biotechnology (KRIBB)
(2022. 6. - 2024. 2.) Researcher, Stem Cell Convergence Research Center (SCCRC), Korea Research Institute for Bioscience and Biotechnology (KRIBB)
(2024. 3. - 2026. 2.) Senior Researcher, Stem Cell Convergence Research Center (SCCRC), Korea Research Institute for Bioscience and Biotechnology (KRIBB)
Research Interests
(1) Development of differentiation and cultivation technologies for human stem cells and organoids
(2) Development of high-efficiency transgenic and genetic engineering technologies for human stem cells and organoids
(3) Construction of human stem cell- and organoid-based biomimetic model systems
(4) Elucidation of molecular mechanisms and discovery of novel therapeutics utilizing biomimetic model systems
(5) Development of next-generation regenerative therapeutics based on human stem cells and organoids
(2) Development of high-efficiency transgenic and genetic engineering technologies for human stem cells and organoids
(3) Construction of human stem cell- and organoid-based biomimetic model systems
(4) Elucidation of molecular mechanisms and discovery of novel therapeutics utilizing biomimetic model systems
(5) Development of next-generation regenerative therapeutics based on human stem cells and organoids
Major Research Achievements
1. Yu WD, Lee SG, Jung KB, Hyun SA, Kim YD, Son YS, Lee H, Cho HS, Kim DS, Lee KJ, Yoo J, Kim C-Y, Lee MO*, Kwon Ohman*, and Son MY*. (2026) Experimental Molecular Medicine (*co-corresponding authors) Accepted in Apr 6 (IF=12.9)
2. Yu WD, Lee S, Cho HS, Kwon Ohman, Lim JH, Jung CR, Jang B, Lee KJ, Yoo J, Kim DS, Lee H, and Son MY. (2026) Experimental Molecular Medicine Feb 12 (IF=12.9)
3. Park SH*, Sun SY, Son JG, Lee SY, Shon HK, Kwon Ohman, Lee M, Choi K, Yeun J, Yoon SH, Son MY, Lee TG, and Lim SG. (2026) Advanced Materials Feb;38(8):e13371 (IF=27.7)
4. Park SH*, Kwon Ohman*, Lee HN*, Cho YH, Yeun JM, Yoon SH, Sun SY, Huh YB, Yu WD, Park SH, Son NE, Jeon SJ, Lee SG, Kim DS, Lee SY, Son JG, Lee KJ, Kim YI, Lim JH, Yoo JM, Lee TG, Son MY, and Lim SG. (2024) Nature Communications 2;15(1):10492 (*These authors contributed equally) (IF=14.7)
5. Son YS*, Kwon YH*, Lee MS*, Kwon Ohman, Jeong YJ, Mun SJ, Jeon SJ, Park JH, Han MH, Bae JS, Hur K, Jang AR, Park JH, Cho HS, Jung CR, Ryu CM, Son MJ, Park DS, and Son MY. (2024) Biomaterials Sep 26:314:122842 (IF=12.8)
6. Cho YH, Lee HN, Jeong WJ, Jung KB, Lee SY, Park SH, Yeun JM, Kwon Ohman, Son JG, Lee TG, Son MY, and Lim SG. (2024) Advanced Materials Sep;36(36):e2403952 (IF=27.7)
7. Kwon Ohman, Jung J, Lee HN, Son YS, Yu WD, Son NE, Lee IC, Kwon HJ, Lee MO, Cho HS, Kim DS, and Son MY. “Chemically defined and scalable culture system for intestinal stem cells derived from human intestinal organoids” (2024) Nature Communications Jan 27;15(1):799 (IF=14.7)
8. Lee HN*, Jung KB*, Ohman Kwon*, Son YS, Choi EH, Yu WD, Son NE, Jeon JH, Jo HN, Yang H, Son YK, Yun CS, Cho HS, Kim SK, Kim DS, Park DS and Son MY. “Limosilactobacillus reuteri DS0384 promotes intestinal epithelial maturation via the postbiotic effect in human intestinal organoids and infant mice” (2022) Gut Microbes Jan-Dec;14(1):2121580 (*These authors contributed equally) (IF=12.2)
9. Ohman Kwon*, Jung KB*, Lee KR*, and Son MY. “The development of a functional human small intestinal epithelium model for drug absorption” (2021) Sci Adv. 7;23:eabh1586 (*These authors contributed equally) (IF=11.7)
2. Yu WD, Lee S, Cho HS, Kwon Ohman, Lim JH, Jung CR, Jang B, Lee KJ, Yoo J, Kim DS, Lee H, and Son MY. (2026) Experimental Molecular Medicine Feb 12 (IF=12.9)
3. Park SH*, Sun SY, Son JG, Lee SY, Shon HK, Kwon Ohman, Lee M, Choi K, Yeun J, Yoon SH, Son MY, Lee TG, and Lim SG. (2026) Advanced Materials Feb;38(8):e13371 (IF=27.7)
4. Park SH*, Kwon Ohman*, Lee HN*, Cho YH, Yeun JM, Yoon SH, Sun SY, Huh YB, Yu WD, Park SH, Son NE, Jeon SJ, Lee SG, Kim DS, Lee SY, Son JG, Lee KJ, Kim YI, Lim JH, Yoo JM, Lee TG, Son MY, and Lim SG. (2024) Nature Communications 2;15(1):10492 (*These authors contributed equally) (IF=14.7)
5. Son YS*, Kwon YH*, Lee MS*, Kwon Ohman, Jeong YJ, Mun SJ, Jeon SJ, Park JH, Han MH, Bae JS, Hur K, Jang AR, Park JH, Cho HS, Jung CR, Ryu CM, Son MJ, Park DS, and Son MY. (2024) Biomaterials Sep 26:314:122842 (IF=12.8)
6. Cho YH, Lee HN, Jeong WJ, Jung KB, Lee SY, Park SH, Yeun JM, Kwon Ohman, Son JG, Lee TG, Son MY, and Lim SG. (2024) Advanced Materials Sep;36(36):e2403952 (IF=27.7)
7. Kwon Ohman, Jung J, Lee HN, Son YS, Yu WD, Son NE, Lee IC, Kwon HJ, Lee MO, Cho HS, Kim DS, and Son MY. “Chemically defined and scalable culture system for intestinal stem cells derived from human intestinal organoids” (2024) Nature Communications Jan 27;15(1):799 (IF=14.7)
8. Lee HN*, Jung KB*, Ohman Kwon*, Son YS, Choi EH, Yu WD, Son NE, Jeon JH, Jo HN, Yang H, Son YK, Yun CS, Cho HS, Kim SK, Kim DS, Park DS and Son MY. “Limosilactobacillus reuteri DS0384 promotes intestinal epithelial maturation via the postbiotic effect in human intestinal organoids and infant mice” (2022) Gut Microbes Jan-Dec;14(1):2121580 (*These authors contributed equally) (IF=12.2)
9. Ohman Kwon*, Jung KB*, Lee KR*, and Son MY. “The development of a functional human small intestinal epithelium model for drug absorption” (2021) Sci Adv. 7;23:eabh1586 (*These authors contributed equally) (IF=11.7)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Drug-induced gastrointestinal toxicity and barrier integrity: cytoskeleton-mediated impairment in a clinically relevant human intestinal epithelium model
Yu, W. D., Lee, S., Cho, H. S., Kwon, O., Lim, J. H., Jung, C. R., Jang, B., Lee, K. J., Yoo, J., Kim, D. S., Lee, H. & Son, M. Y., Mar 2026, In: Experimental and Molecular Medicine. 58, 2, p. 487-500 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Tailored Xenogeneic-Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells
Park, S., Sun, S. Y., Son, J. G., Lee, S. Y., Shon, H. K., Kwon, O., Lee, M., Choi, K., Yeun, J., Yoon, S. H., Kim, M., Son, M. Y., Lee, T. G. & Im, S. G., 6 Feb 2026, In: Advanced Materials. 38, 8, e13371.Research output: Contribution to journal › Article › peer-review
Open Access -
Helicobacter pylori VacA-induced mitochondrial damage in the gastric pit cells of the antrum and therapeutic rescue
Son, Y. S., Kwon, Y. H., Lee, M. S., Kwon, O., Jeong, Y. J., Mun, S. J., Jeon, S., Park, J. H., Han, M. H., Bae, J. S., Hur, K., Jang, A. R., Park, J. H., Cho, H. S., Jung, C. R., Ryu, C. M., Son, M. J., Park, D. S. & Son, M. Y., Mar 2025, In: Biomaterials. 314, 122842.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Chemically-defined and scalable culture system for intestinal stem cells derived from human intestinal organoids
Kwon, O., Lee, H., Jung, J., Son, Y. S., Jeon, S., Yoo, W. D., Son, N., Jung, K. B., Choi, E., Lee, I. C., Kwon, H. J., Kim, C., Lee, M. O., Cho, H. S., Kim, D. S. & Son, M. Y., 27 Jan 2024, In: Nature Communications. 15, 1, 799.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Long-Term Culture of Human Pluripotent Stem Cells in Xeno-Free Condition Using Functional Polymer Films
Cho, Y., Lee, H., Jeong, W., Jung, K. B., Lee, S. Y., Park, S., Yeun, J., Kwon, O., Son, J. G., Lee, T. G., Son, M. Y. & Im, S. G., 5 Sep 2024, In: Advanced Materials. 36, 36, 2403952.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations