@inproceedings{3b5ca12f370a4a22bbfdf5a4dd446630,
title = "A nanofluidic device for selective concentration and label-free surface-enhanced raman detection of protein aggregates implicated in neurodegeneration",
abstract = "This work demonstrates an advanced method for highly selective concentration and sensitive label-free detection of protein aggregates, using a nanofluidic device with surface-enhanced Raman scattering (SERS) active substrate. In our previous work [1], we reported proof-of-concept results for a new type of nanofluidic device rapid prototyping using elastomeric collapse. Here, we present a practical application of this system by showing its ability to detect and characterize small amounts of protein aggregates, which are strongly implicated in several clinically and pathologically distinct diseases.",
keywords = "Label-free characterization, Nanofluidic device, Neurodegeneration, Protein aggregate",
author = "Inhee Choi and Huh, {Yun Suk} and David Erickson",
year = "2010",
language = "English",
isbn = "9781618390622",
series = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
pages = "476--478",
booktitle = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
note = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 ; Conference date: 03-10-2010 Through 07-10-2010",
}