A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer

Yura Kim; Ji Youn Park; Hye Young Kim; Minzae Lee; Jongheop Yi; Inhee Choi

doi:10.1039/c5cc05327g

A single nanoparticle-based sensor for hydrogen peroxide (H₂O₂) via cytochrome c-mediated plasmon resonance energy transfer

Yura Kim, Ji Youn Park, Hye Young Kim, Minzae Lee, Jongheop Yi, Inhee Choi

Department of Life Science

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Herein, we report a novel method for H₂O₂ detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H₂O₂. Based on the changes in the spectral profile of the single plasmonic nanoprobe, H₂O₂ was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations.

Original language	English
Pages (from-to)	15370-15373
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	84
DOIs	https://doi.org/10.1039/c5cc05327g
State	Published - 2015

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title = "A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer",

abstract = "Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H2O2. Based on the changes in the spectral profile of the single plasmonic nanoprobe, H2O2 was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations.",

author = "Yura Kim and Park, {Ji Youn} and Kim, {Hye Young} and Minzae Lee and Jongheop Yi and Inhee Choi",

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year = "2015",

doi = "10.1039/c5cc05327g",

language = "English",

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pages = "15370--15373",

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T1 - A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer

AU - Kim, Yura

AU - Park, Ji Youn

AU - Kim, Hye Young

AU - Lee, Minzae

AU - Yi, Jongheop

AU - Choi, Inhee

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015

Y1 - 2015

N2 - Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H2O2. Based on the changes in the spectral profile of the single plasmonic nanoprobe, H2O2 was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations.

AB - Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H2O2. Based on the changes in the spectral profile of the single plasmonic nanoprobe, H2O2 was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations.

UR - http://www.scopus.com/inward/record.url?scp=84943781364&partnerID=8YFLogxK

U2 - 10.1039/c5cc05327g

DO - 10.1039/c5cc05327g

M3 - Article

C2 - 26327303

AN - SCOPUS:84943781364

SN - 1359-7345

VL - 51

SP - 15370

EP - 15373

JO - Chemical Communications

JF - Chemical Communications

IS - 84

ER -

A single nanoparticle-based sensor for hydrogen peroxide (H₂O₂) via cytochrome c-mediated plasmon resonance energy transfer

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