A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer

Yura Kim, Ji Youn Park, Hye Young Kim, Minzae Lee, Jongheop Yi, Inhee Choi

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H2O2. Based on the changes in the spectral profile of the single plasmonic nanoprobe, H2O2 was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations.

Original languageEnglish
Pages (from-to)15370-15373
Number of pages4
JournalChemical Communications
Volume51
Issue number84
DOIs
StatePublished - 2015

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