TY - JOUR
T1 - Active Demethylation of Cancer Cells using Terahertz Radiation for Potential Cancer Treatment
AU - Son, Joo Hiuk
N1 - Publisher Copyright:
© IEEE 2022.
PY - 2022
Y1 - 2022
N2 - Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer before genetic mutation. Because the abnormal DNA methylation is found in most cancer cells, the assessment of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. The methylation has been directly observed by terahertz time-domain spectroscopy and this epigenetic chemical change could be manipulated to the state of demethylation using resonant terahertz radiation. Demethylation of cancer cells is a key issue in epigenetic cancer therapy and our results may lead to the treatment of cancer using electromagnetic waves.
AB - Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer before genetic mutation. Because the abnormal DNA methylation is found in most cancer cells, the assessment of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. The methylation has been directly observed by terahertz time-domain spectroscopy and this epigenetic chemical change could be manipulated to the state of demethylation using resonant terahertz radiation. Demethylation of cancer cells is a key issue in epigenetic cancer therapy and our results may lead to the treatment of cancer using electromagnetic waves.
UR - http://www.scopus.com/inward/record.url?scp=85166480184&partnerID=8YFLogxK
U2 - 10.1364/CLEOPR.2022.CMP3A_02
DO - 10.1364/CLEOPR.2022.CMP3A_02
M3 - Conference article
AN - SCOPUS:85166480184
SN - 2162-2701
JO - Optics InfoBase Conference Papers
JF - Optics InfoBase Conference Papers
T2 - 2022 Conference on Lasers and Electro-Optics Pacific Rim, CLEO/PR 2022
Y2 - 31 August 2022 through 5 September 2022
ER -
