Active Demethylation of Cancer Cells using Terahertz Radiation for Potential Cancer Treatment

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer before genetic mutation. Because the abnormal DNA methylation is found in most cancer cells, the assessment of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. The methylation has been directly observed by terahertz time-domain spectroscopy and this epigenetic chemical change could be manipulated to the state of demethylation using resonant terahertz radiation. Demethylation of cancer cells is a key issue in epigenetic cancer therapy and our results may lead to the treatment of cancer using electromagnetic waves.

Original languageEnglish
Title of host publication2022 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2022 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798350350012
DOIs
StatePublished - 2022
Event2022 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2022 - Sapparo, Japan
Duration: 31 Jul 20225 Aug 2022

Publication series

Name2022 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2022 - Proceedings

Conference

Conference2022 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2022
Country/TerritoryJapan
CitySapparo
Period31/07/225/08/22

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