Assessment of degradation behavior for acetylsalicylic acid using a plasma in liquid process

Hye Jin Bang, Heon Lee, Young Kwon Park, Hyung Ho Ha, Young Hyun Yu, Byung Joo Kim, Sang Chul Jung

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Acetylsalicylic acid (ASA) is a pharmacologically active compound. In this study, ASA was decomposed effectively using a plasma in liquid phase process with hydrogen peroxide and TiO2 photocatalyst. Increasing the electrical power conditions (frequency, applied voltage, and pulse width) promoted plasma generation, which increased the rate of ASA decomposition. The added hydrogen peroxide increased the rate of ASA degradation, but injecting an excess decreased the degradation rate due to a scavenger effect. Although there was an initial increase in the decomposition efficiency by the addition of TiO2 powder, the addition of an excessive amount inhibited the generation of plasma and decreased the degradation rate. The simultaneous addition of H2O2 and TiO2 powder resulted in the highest degradation efficiency. We suggest that ASA is converted to salicylic acid through demethylation by hydroxyl radicals and is finally mineralized to carbon dioxide and water via 2,4-dihydroxy benzoic acid and low molecular acids.

Original languageEnglish
Article number965
Issue number11
StatePublished - Nov 2019


  • Acetylsalicylic acid
  • Decomposition mechanism
  • Hydrogen peroxide
  • Plasma in liquid phase process
  • TiO photocatalyst


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