Dictionary learning and sparse coding-based denoising for high-resolution task functional connectivity MRI analysis

Seongah Jeong, Xiang Li, Jiarui Yang, Quanzheng Li, Vahid Tarokh

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

6 Scopus citations

Abstract

We propose a novel denoising framework for task functional Magnetic Resonance Imaging (tfMRI) data to delineate the high-resolution spatial pattern of the brain functional connectivity via dictionary learning and sparse coding (DLSC). In order to address the limitations of the unsupervised DLSC-based fMRI studies, we utilize the prior knowledge of task paradigm in the learning step to train a data-driven dictionary and to model the sparse representation. We apply the proposed DLSC-based method to Human Connectome Project (HCP) motor tfMRI dataset. Studies on the functional connectivity of cerebrocerebellar circuits in somatomotor networks show that the DLSC-based denoising framework can significantly improve the prominent connectivity patterns, in comparison to the temporal non-local means (tNLM)-based denoising method as well as the case without denoising, which is consistent and neuroscientifically meaningful within motor area. The promising results show that the proposed method can provide an important foundation for the high-resolution functional connectivity analysis, and provide a better approach for fMRI preprocessing.

Original languageEnglish
Title of host publicationMachine Learning in Medical Imaging - 8th International Workshop, MLMI 2017, Held in Conjunction with MICCAI 2017, Proceedings
EditorsYinghuan Shi, Heung-Il Suk, Kenji Suzuki, Qian Wang
PublisherSpringer Verlag
Pages45-52
Number of pages8
ISBN (Print)9783319673882
DOIs
StatePublished - 2017
Event8th International Workshop on Machine Learning in Medical Imaging, MLMI 2017 held in conjunction with the 20th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2017 - Quebec City, Canada
Duration: 10 Sep 201710 Sep 2017

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume10541 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference8th International Workshop on Machine Learning in Medical Imaging, MLMI 2017 held in conjunction with the 20th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2017
Country/TerritoryCanada
CityQuebec City
Period10/09/1710/09/17

Keywords

  • Connectivity
  • Denoising
  • Dictionary learning
  • Functional magnetic resonance imaging (fMRI)
  • Sparse coding

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