DNA hydrogel microspheres and their potential applications for protein delivery and live cell monitoring

Taeyoung Kim; Seongmin Park; Minhyuk Lee; Solhee Baek; Jong Bum Lee; Nokyoung Park

doi:10.1063/1.4953046

DNA hydrogel microspheres and their potential applications for protein delivery and live cell monitoring

Taeyoung Kim, Seongmin Park, Minhyuk Lee, Solhee Baek, Jong Bum Lee, Nokyoung Park

Department of Chemical Engineering

Myongji University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Microfluidic devices have been extensively developed as methods for microscale materials fabrication. It has also been adopted for polymeric microsphere fabrication and in situ drug encapsulation. Here, we employed multi-inlet microfluidic channels for DNA hydrogel microsphere formation and in situ protein encapsulation. The release of encapsulated proteins from DNA hydrogels showed different profiles accordingly with the size of microspheres.

Original language	English
Article number	034112
Journal	Biomicrofluidics
Volume	10
Issue number	3
DOIs	https://doi.org/10.1063/1.4953046
State	Published - 1 May 2016

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abstract = "Microfluidic devices have been extensively developed as methods for microscale materials fabrication. It has also been adopted for polymeric microsphere fabrication and in situ drug encapsulation. Here, we employed multi-inlet microfluidic channels for DNA hydrogel microsphere formation and in situ protein encapsulation. The release of encapsulated proteins from DNA hydrogels showed different profiles accordingly with the size of microspheres.",

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AU - Park, Seongmin

AU - Lee, Minhyuk

AU - Baek, Solhee

AU - Lee, Jong Bum

AU - Park, Nokyoung

PY - 2016/5/1

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AB - Microfluidic devices have been extensively developed as methods for microscale materials fabrication. It has also been adopted for polymeric microsphere fabrication and in situ drug encapsulation. Here, we employed multi-inlet microfluidic channels for DNA hydrogel microsphere formation and in situ protein encapsulation. The release of encapsulated proteins from DNA hydrogels showed different profiles accordingly with the size of microspheres.

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DNA hydrogel microspheres and their potential applications for protein delivery and live cell monitoring

Abstract

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