TY - JOUR
T1 - Effects of physical (hypoxia, hyperoxia) and chemical (potassium dichromate, fenitrothion) stress on antioxidant enzyme activities in Chironomus riparius Mg. (Diptera, Chironomidae) larvae
T2 - Potential biomarkers
AU - Choi, Jinhee
AU - Roche, Hélène
AU - Caquet, Thierry
PY - 2000
Y1 - 2000
N2 - Effects of physical (hypoxia, hyperoxia) and chemical (potassium dichromate, fenitrothion) stress on antioxidant enzyme activities and hemoglobin content in Chironomus riparius Mg. (Diptera, Chironomidae) larvae were evaluated under laboratory conditions in order to identify pertinent biomarkers of stress. Hypoxia and hyperoxia caused an increase in Cu,Zn- superoxide dismutase (SOD) and Mn-SOD activities and a simultaneous decrease in total peroxidase (Px) and glutathione peroxidase (GSHPx) activities. A parallel increase in hemoglobin concentration in the hemolymph was observed. The exposure to sublethal concentrations of both potassium dichromate and fenitrothion led to an increase in Cu,Zn-SOD and Mn-SOD activities and to a decrease in GSH-Px activity. Activation of catalase (CAT) was observed in the larvae exposed to high fenitrothion concentration (μg/L). The response of SODs was rapid and sensitive to low chemical concentrations, but changes in CAT, Px, and GSH-Px were more specific and less sensitive.
AB - Effects of physical (hypoxia, hyperoxia) and chemical (potassium dichromate, fenitrothion) stress on antioxidant enzyme activities and hemoglobin content in Chironomus riparius Mg. (Diptera, Chironomidae) larvae were evaluated under laboratory conditions in order to identify pertinent biomarkers of stress. Hypoxia and hyperoxia caused an increase in Cu,Zn- superoxide dismutase (SOD) and Mn-SOD activities and a simultaneous decrease in total peroxidase (Px) and glutathione peroxidase (GSHPx) activities. A parallel increase in hemoglobin concentration in the hemolymph was observed. The exposure to sublethal concentrations of both potassium dichromate and fenitrothion led to an increase in Cu,Zn-SOD and Mn-SOD activities and to a decrease in GSH-Px activity. Activation of catalase (CAT) was observed in the larvae exposed to high fenitrothion concentration (μg/L). The response of SODs was rapid and sensitive to low chemical concentrations, but changes in CAT, Px, and GSH-Px were more specific and less sensitive.
KW - Antioxidant enzymes Biomarkers of stress
KW - Chironomus riparius
KW - Fenitrothion
KW - Potassium dichromate
UR - http://www.scopus.com/inward/record.url?scp=0034107817&partnerID=8YFLogxK
U2 - 10.1002/etc.5620190231
DO - 10.1002/etc.5620190231
M3 - Article
AN - SCOPUS:0034107817
SN - 0730-7268
VL - 19
SP - 495
EP - 500
JO - Environmental Toxicology and Chemistry
JF - Environmental Toxicology and Chemistry
IS - 2
ER -