Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies:: In vivo imaging of diesel exhaust particulates in mice

Chang Heon Lee; Ha Eun Shim; Lee Song; Hi Gyu Moon; Kyuhong Lee; Jung Eun Yang; Ha Yeon Song; Yong Jun Choi; Dae Seong Choi; Jongho Jeon

doi:10.1039/c8cc08304e

Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies:: In vivo imaging of diesel exhaust particulates in mice

Chang Heon Lee
, Ha Eun Shim
, Lee Song
, Hi Gyu Moon
, Kyuhong Lee
, Jung Eun Yang
, Ha Yeon Song
, Yong Jun Choi
, Dae Seong Choi
, Jongho Jeon

School of Environmental Engineering

Korea Atomic Energy Research Institute
Korea Institute of Toxicology
World Institute of Kimchi
University of Science and Technology UST

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

As a robust radioanalytical method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue. Single-photon emission computed tomography and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity.

Original language	English
Pages (from-to)	447-450
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	4
DOIs	https://doi.org/10.1039/c8cc08304e
State	Published - 2019

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title = "Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies:: In vivo imaging of diesel exhaust particulates in mice",

abstract = "As a robust radioanalytical method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue. Single-photon emission computed tomography and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity.",

author = "Lee, \{Chang Heon\} and Shim, \{Ha Eun\} and Lee Song and Moon, \{Hi Gyu\} and Kyuhong Lee and Yang, \{Jung Eun\} and Song, \{Ha Yeon\} and Choi, \{Yong Jun\} and Choi, \{Dae Seong\} and Jongho Jeon",

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doi = "10.1039/c8cc08304e",

language = "English",

volume = "55",

pages = "447--450",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies:: In vivo imaging of diesel exhaust particulates in mice

AU - Lee, Chang Heon

AU - Shim, Ha Eun

AU - Song, Lee

AU - Moon, Hi Gyu

AU - Lee, Kyuhong

AU - Yang, Jung Eun

AU - Song, Ha Yeon

AU - Choi, Yong Jun

AU - Choi, Dae Seong

AU - Jeon, Jongho

PY - 2019

Y1 - 2019

N2 - As a robust radioanalytical method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue. Single-photon emission computed tomography and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity.

AB - As a robust radioanalytical method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue. Single-photon emission computed tomography and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity.

UR - https://www.scopus.com/pages/publications/85059498005

U2 - 10.1039/c8cc08304e

DO - 10.1039/c8cc08304e

M3 - Article

C2 - 30474665

AN - SCOPUS:85059498005

SN - 1359-7345

VL - 55

SP - 447

EP - 450

JO - Chemical Communications

JF - Chemical Communications

IS - 4

ER -

Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies:: In vivo imaging of diesel exhaust particulates in mice

Abstract

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