Highly selective detection of Cu2+ utilizing specific binding between Cu-demetallated superoxide dismutase 1 and the Cu2+ ion via surface plasmon resonance spectroscopy

  • Suseung Lee
  • , Inhee Choi
  • , Surin Hong
  • , Young In Yang
  • , Jeongjin Lee
  • , Taewook Kang
  • , Jongheop Yi

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

A highly specific interaction between a metal-deficient metalloenzyme and metal ion has been utilized in the selective detection of the metal ion by surface plasmon resonance spectroscopy (SPRS). The use of SPRS and Cu-demetallated superoxide dismutase (E,Zn-SOD1) as a sensing actuator allows one to selectively and in situ detect Cu2+ without any interference that other spectroscopic methods may have.

Original languageEnglish
Pages (from-to)6171-6173
Number of pages3
JournalChemical Communications
Issue number41
DOIs
StatePublished - 2009

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