Nanoslit confined DNA at low ionic strengths

Jinyong Lee; Sulhwa Kim; Huisu Jeong; Gun Young Jung; Rakwoo Chang; Yeng Long Chen; Kyubong Jo

doi:10.1021/mz500396t

Nanoslit confined DNA at low ionic strengths

Jinyong Lee, Sulhwa Kim, Huisu Jeong, Gun Young Jung, Rakwoo Chang, Yeng Long Chen, Kyubong Jo

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

We present nanoslit confined DNA conformations at very low ionic strengths and a theory to explain most measurements for single DNA molecule size under strong nanoslit confinement. Very low ionic strength conditions not only increase the DNA persistence length dramatically, but also cause DNA molecules to swell to the extent that the effective diameter of DNA becomes larger than the nanoslit height. By accounting for these effects, our results and theory provide a reasonable clue for a current controversy regarding the dependence of the DNA conformation on slit height (h), persistence length (p), and e ffective diameter (w). (Figure Presented).

Original language	English
Pages (from-to)	926-930
Number of pages	5
Journal	ACS Macro Letters
Volume	3
Issue number	9
DOIs	https://doi.org/10.1021/mz500396t
State	Published - 16 Sep 2014

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@article{d25f8c4e88fc43cf9a9d86e8abce7842,

title = "Nanoslit confined DNA at low ionic strengths",

abstract = "We present nanoslit confined DNA conformations at very low ionic strengths and a theory to explain most measurements for single DNA molecule size under strong nanoslit confinement. Very low ionic strength conditions not only increase the DNA persistence length dramatically, but also cause DNA molecules to swell to the extent that the effective diameter of DNA becomes larger than the nanoslit height. By accounting for these effects, our results and theory provide a reasonable clue for a current controversy regarding the dependence of the DNA conformation on slit height (h), persistence length (p), and e ffective diameter (w). (Figure Presented).",

author = "Jinyong Lee and Sulhwa Kim and Huisu Jeong and Jung, {Gun Young} and Rakwoo Chang and Chen, {Yeng Long} and Kyubong Jo",

note = "Publisher Copyright: {\textcopyright} 2014 American Chemical Society.",

year = "2014",

month = sep,

day = "16",

doi = "10.1021/mz500396t",

language = "English",

volume = "3",

pages = "926--930",

journal = "ACS Macro Letters",

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TY - JOUR

T1 - Nanoslit confined DNA at low ionic strengths

AU - Lee, Jinyong

AU - Kim, Sulhwa

AU - Jeong, Huisu

AU - Jung, Gun Young

AU - Chang, Rakwoo

AU - Chen, Yeng Long

AU - Jo, Kyubong

PY - 2014/9/16

Y1 - 2014/9/16

N2 - We present nanoslit confined DNA conformations at very low ionic strengths and a theory to explain most measurements for single DNA molecule size under strong nanoslit confinement. Very low ionic strength conditions not only increase the DNA persistence length dramatically, but also cause DNA molecules to swell to the extent that the effective diameter of DNA becomes larger than the nanoslit height. By accounting for these effects, our results and theory provide a reasonable clue for a current controversy regarding the dependence of the DNA conformation on slit height (h), persistence length (p), and e ffective diameter (w). (Figure Presented).

AB - We present nanoslit confined DNA conformations at very low ionic strengths and a theory to explain most measurements for single DNA molecule size under strong nanoslit confinement. Very low ionic strength conditions not only increase the DNA persistence length dramatically, but also cause DNA molecules to swell to the extent that the effective diameter of DNA becomes larger than the nanoslit height. By accounting for these effects, our results and theory provide a reasonable clue for a current controversy regarding the dependence of the DNA conformation on slit height (h), persistence length (p), and e ffective diameter (w). (Figure Presented).

UR - http://www.scopus.com/inward/record.url?scp=84915784623&partnerID=8YFLogxK

U2 - 10.1021/mz500396t

DO - 10.1021/mz500396t

M3 - Article

AN - SCOPUS:84915784623

SN - 2161-1653

VL - 3

SP - 926

EP - 930

JO - ACS Macro Letters

JF - ACS Macro Letters

IS - 9

ER -

Nanoslit confined DNA at low ionic strengths

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