@inproceedings{c83974b1f03141c698cad3fcd3d418f1,
title = "Terahertz demethylation for cancer therapy",
abstract = "Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer before genetic mutation. Because the abnormal DNA methylation is found in most cancer cells, the assessment of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. The methylation has been directly observed by terahertz time-domain spectroscopy and this epigenetic chemical change could be manipulated to the state of demethylation using resonant terahertz radiation. Demethylation of cancer cells is a key issue in epigenetic cancer therapy and our results demonstrate the feasibility of the cancer treatment using optical technique.",
keywords = "cancer imaging, cancer therapy, DNA methylation, Terahertz radiation, terahertz spectroscopy",
author = "Son, {Joo Hiuk}",
note = "Publisher Copyright: {\textcopyright} 2024 SPIE.; Terahertz Emitters, Receivers, and Applications XV 2024 ; Conference date: 18-08-2024 Through 19-08-2024",
year = "2024",
doi = "10.1117/12.3028792",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Manijeh Razeghi and Mona Jarrahi",
booktitle = "Terahertz Emitters, Receivers, and Applications XV",
address = "United States",
}
