TY - JOUR
T1 - Terahertz Radiation for Demethylation of Cancer Cells
AU - Son, Joo Hiuk
N1 - Publisher Copyright:
© The Authors, published by EDP Sciences.
PY - 2024/10/31
Y1 - 2024/10/31
N2 - Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer before genetic mutation. Because the abnormal DNA methylation is found in most cancer cells, the assessment of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. The methylation has been directly observed by terahertz time-domain spectroscopy and this epigenetic chemical change could be manipulated to the state of demethylation using resonant terahertz radiation. Demethylation of cancer cells is a key issue in epigenetic cancer therapy and our results demonstrate the feasibility of the cancer treatment using optical technique.
AB - Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer before genetic mutation. Because the abnormal DNA methylation is found in most cancer cells, the assessment of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. The methylation has been directly observed by terahertz time-domain spectroscopy and this epigenetic chemical change could be manipulated to the state of demethylation using resonant terahertz radiation. Demethylation of cancer cells is a key issue in epigenetic cancer therapy and our results demonstrate the feasibility of the cancer treatment using optical technique.
UR - https://www.scopus.com/pages/publications/85212477519
U2 - 10.1051/epjconf/202430904024
DO - 10.1051/epjconf/202430904024
M3 - Conference article
AN - SCOPUS:85212477519
SN - 2101-6275
VL - 309
JO - EPJ Web of Conferences
JF - EPJ Web of Conferences
M1 - 04024
T2 - 2024 EOS Annual Meeting, EOSAM 2024
Y2 - 9 September 2024 through 13 September 2024
ER -
