Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

Young Bin Ji; Sang Hoon Kim; Kiyoung Jeong; Yuna Choi; Joo Hiuk Son; Dong Woo Park; Sam Kyu Noh; Tae In Jeon; Yong Min Huh; Seungjoo Haam; Sang Kil Lee; Seung Jae Oh; Jin Suck Suh

doi:10.1364/BOE.5.004162

Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

Young Bin Ji, Sang Hoon Kim, Kiyoung Jeong, Yuna Choi, Joo Hiuk Son, Dong Woo Park, Sam Kyu Noh, Tae In Jeon, Yong Min Huh, Seungjoo Haam, Sang Kil Lee, Seung Jae Oh, Jin Suck Suh

Department of Physics

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.

Original language	English
Article number	A4162
Pages (from-to)	4162-4170
Number of pages	9
Journal	Biomedical Optics Express
Volume	5
Issue number	12
DOIs	https://doi.org/10.1364/BOE.5.004162
State	Published - 2014

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title = "Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model",

abstract = "We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.",

author = "Ji, {Young Bin} and Kim, {Sang Hoon} and Kiyoung Jeong and Yuna Choi and Son, {Joo Hiuk} and Park, {Dong Woo} and Noh, {Sam Kyu} and Jeon, {Tae In} and Huh, {Yong Min} and Seungjoo Haam and Lee, {Sang Kil} and Oh, {Seung Jae} and Suh, {Jin Suck}",

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year = "2014",

doi = "10.1364/BOE.5.004162",

language = "English",

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T1 - Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

AU - Ji, Young Bin

AU - Kim, Sang Hoon

AU - Jeong, Kiyoung

AU - Choi, Yuna

AU - Son, Joo Hiuk

AU - Park, Dong Woo

AU - Noh, Sam Kyu

AU - Jeon, Tae In

AU - Huh, Yong Min

AU - Haam, Seungjoo

AU - Lee, Sang Kil

AU - Oh, Seung Jae

AU - Suh, Jin Suck

PY - 2014

Y1 - 2014

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AB - We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.

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Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

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