Terahertz spectroscopic imaging of a rabbit VX2 hepatoma model

Jae Yeon Park; Hyuck Jae Choi; Kyoung Sik Cho; Kyu Rae Kim; Joo Hiuk Son

doi:10.1063/1.3551575

Terahertz spectroscopic imaging of a rabbit VX2 hepatoma model

Jae Yeon Park, Hyuck Jae Choi, Kyoung Sik Cho, Kyu Rae Kim, Joo Hiuk Son

Department of Physics

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32 Scopus citations

Abstract

Terahertz (THz) spectroscopic imaging technique was applied to classify the tumor region in the rabbit liver with VX2 hepatocellular carcinoma. Within the measurement range of 0.1-2 THz, the average reflectance values for all tumor samples were more than 4 higher than those for healthy cells, and the terahertz measurements correlated well with histological analysis results. This study on paraffin-embedded tissues showed the alteration of cell density and protein content in tumors, excluding the effect of water.

Original language	English
Article number	064704
Journal	Journal of Applied Physics
Volume	109
Issue number	6
DOIs	https://doi.org/10.1063/1.3551575
State	Published - 15 Mar 2011

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abstract = "Terahertz (THz) spectroscopic imaging technique was applied to classify the tumor region in the rabbit liver with VX2 hepatocellular carcinoma. Within the measurement range of 0.1-2 THz, the average reflectance values for all tumor samples were more than 4 higher than those for healthy cells, and the terahertz measurements correlated well with histological analysis results. This study on paraffin-embedded tissues showed the alteration of cell density and protein content in tumors, excluding the effect of water.",

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AU - Son, Joo Hiuk

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AB - Terahertz (THz) spectroscopic imaging technique was applied to classify the tumor region in the rabbit liver with VX2 hepatocellular carcinoma. Within the measurement range of 0.1-2 THz, the average reflectance values for all tumor samples were more than 4 higher than those for healthy cells, and the terahertz measurements correlated well with histological analysis results. This study on paraffin-embedded tissues showed the alteration of cell density and protein content in tumors, excluding the effect of water.

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Terahertz spectroscopic imaging of a rabbit VX2 hepatoma model

Abstract

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