Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA

Joo Hiuk Son, Hwayeong Cheon

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer occurring before genetic mutation. Because the abnormal DNA methylation is found in most of cancer cells, the detection and manipulation of DNA methylation using terahertz radiation can be a novel pioneering method in cancer study. The DNA methylation has been directly observed by terahertz spectroscopy at around 1.65 THz and this epigenetic chemical change could be manipulated to the state of demethylation using a high-power terahertz radiation. Demethylation of cancer DNA is a key problem in epigenetic cancer therapy and our results may lead to the treatment of cancer in early stage.

Original languageEnglish
Title of host publication2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
PublisherIEEE Computer Society
ISBN (Electronic)9781538638095
DOIs
StatePublished - 25 Oct 2018
Event43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018 - Nagoya, Japan
Duration: 9 Sep 201814 Sep 2018

Publication series

NameInternational Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
Volume2018-September
ISSN (Print)2162-2027
ISSN (Electronic)2162-2035

Conference

Conference43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
Country/TerritoryJapan
CityNagoya
Period9/09/1814/09/18

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