Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA

Joo Hiuk Son; Hwayeong Cheon

doi:10.1109/IRMMW-THz.2018.8510290

Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA

Joo Hiuk Son
, Hwayeong Cheon

Department of Physics

University of Seoul

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer occurring before genetic mutation. Because the abnormal DNA methylation is found in most of cancer cells, the detection and manipulation of DNA methylation using terahertz radiation can be a novel pioneering method in cancer study. The DNA methylation has been directly observed by terahertz spectroscopy at around 1.65 THz and this epigenetic chemical change could be manipulated to the state of demethylation using a high-power terahertz radiation. Demethylation of cancer DNA is a key problem in epigenetic cancer therapy and our results may lead to the treatment of cancer in early stage.

Original language	English
Title of host publication	2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
Publisher	IEEE Computer Society
ISBN (Electronic)	9781538638095
DOIs	https://doi.org/10.1109/IRMMW-THz.2018.8510290
State	Published - 25 Oct 2018
Event	43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018 - Nagoya, Japan Duration: 9 Sep 2018 → 14 Sep 2018

Publication series

Name	International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
Volume	2018-September
ISSN (Print)	2162-2027
ISSN (Electronic)	2162-2035

Conference

Conference	43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
Country/Territory	Japan
City	Nagoya
Period	9/09/18 → 14/09/18

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1109/IRMMW-THz.2018.8510290

Cite this

Son, J. H., & Cheon, H. (2018). Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA. In 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018 Article 8510290 (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz; Vol. 2018-September). IEEE Computer Society. https://doi.org/10.1109/IRMMW-THz.2018.8510290

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title = "Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA",

abstract = "Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer occurring before genetic mutation. Because the abnormal DNA methylation is found in most of cancer cells, the detection and manipulation of DNA methylation using terahertz radiation can be a novel pioneering method in cancer study. The DNA methylation has been directly observed by terahertz spectroscopy at around 1.65 THz and this epigenetic chemical change could be manipulated to the state of demethylation using a high-power terahertz radiation. Demethylation of cancer DNA is a key problem in epigenetic cancer therapy and our results may lead to the treatment of cancer in early stage.",

author = "Son, \{Joo Hiuk\} and Hwayeong Cheon",

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year = "2018",

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doi = "10.1109/IRMMW-THz.2018.8510290",

language = "English",

series = "International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz",

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Son, JH & Cheon, H 2018, Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA. in 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018., 8510290, International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz, vol. 2018-September, IEEE Computer Society, 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018, Nagoya, Japan, 9/09/18. https://doi.org/10.1109/IRMMW-THz.2018.8510290

Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA. / Son, Joo Hiuk; Cheon, Hwayeong.
2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018. IEEE Computer Society, 2018. 8510290 (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz; Vol. 2018-September).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Toward Cancer Treatment Using Terahertz Radiation

T2 - 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018

AU - Son, Joo Hiuk

AU - Cheon, Hwayeong

PY - 2018/10/25

Y1 - 2018/10/25

N2 - Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer occurring before genetic mutation. Because the abnormal DNA methylation is found in most of cancer cells, the detection and manipulation of DNA methylation using terahertz radiation can be a novel pioneering method in cancer study. The DNA methylation has been directly observed by terahertz spectroscopy at around 1.65 THz and this epigenetic chemical change could be manipulated to the state of demethylation using a high-power terahertz radiation. Demethylation of cancer DNA is a key problem in epigenetic cancer therapy and our results may lead to the treatment of cancer in early stage.

AB - Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer occurring before genetic mutation. Because the abnormal DNA methylation is found in most of cancer cells, the detection and manipulation of DNA methylation using terahertz radiation can be a novel pioneering method in cancer study. The DNA methylation has been directly observed by terahertz spectroscopy at around 1.65 THz and this epigenetic chemical change could be manipulated to the state of demethylation using a high-power terahertz radiation. Demethylation of cancer DNA is a key problem in epigenetic cancer therapy and our results may lead to the treatment of cancer in early stage.

UR - https://www.scopus.com/pages/publications/85056825627

U2 - 10.1109/IRMMW-THz.2018.8510290

DO - 10.1109/IRMMW-THz.2018.8510290

M3 - Conference contribution

AN - SCOPUS:85056825627

T3 - International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz

BT - 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018

PB - IEEE Computer Society

Y2 - 9 September 2018 through 14 September 2018

ER -

Toward Cancer Treatment Using Terahertz Radiation: Demethylation of Cancer DNA

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