Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: A potential role for protein aggregation in autophagic substrate selection

Brigit E. Riley, Stephen E. Kaiser, Thomas A. Shaler, Aylwin C.Y. Ng, Taichi Hara, Mark S. Hipp, Kasper Lage, Ramnik J. Xavier, Kwon Yul Ryu, Keiko Taguchi, Masayuki Yamamoto, Keiji Tanaka, Noboru Mizushima, Masaaki Komatsu, Ron R. Kopito

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Biochemistry, Genetics and Molecular Biology